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Why Does Wine Sometimes Cause Headaches?

If it’s not a hangover, then what is it?

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Recipes engineered for perfection—what exactly does that mean? We take you inside Cook’s Illustrated’s science experiments.


THE BACKSTORY

If you drink more than three glasses of wine and wake up with a headache, then what you’re experiencing is probably a hangover. We can’t help you with that, other than to suggest going for a run and drinking a lot of water. But if you’ve only had one glass and you get a headache afterwards, then something else is going on. A reader wrote in wondering why this happens, so we took it upon ourselves to get to the cause of the pain.

THE INVESTIGATION

The culprits, it turns out, are either sulfites or amines. Grape skins not only host the yeast that ferments grapes into wine, but also contain vinegar bacteria that can spoil new wine. Some vintners add sulfites (sulfur dioxide and its salts) to help stop their goods from spoiling. Many foods have sulfites added as a preservative because they inhibit the growth of molds and bacteria, stop oxidation (browning), and also preserve wine’s natural flavor.

But if you’re allergic to sulfites, you’d also be allergic to a number of other foods, like crackers, pizza crust, canned tuna, pickles, olives, shrimp, and dried fruit. So if you get headaches when you drink wine but not when you eat the foods above, you can rule out sulfites as the reason. For those of you who are allergic to sulfites, try drinking organic wines. They are, by definition, sulfite-free.

If it’s not a hangover, and you’re not allergic to sulfites, that leaves amines, a naturally occurring compound in fermented foods and beverages. Wine contains two kinds of amines, histamines and tyramines; histamines dilate blood vessels in the brain, while tyramines constrict them. Both of these actions can cause headaches in people who are sensitive to one or both of the chemicals. Other foods with higher amine counts are cheese, sauerkraut, salami, flour tortillas, sourdough breads, horseradish, and maraschino cherries. If you also get a headache after eating any of those foods, amines may be the cause.

MAKE IT NOW: Our recipe for Red Wine-Braised Pork Chops is free through February 5, 2013.

About the Author: America's Test Kitchen

We're the cooks, editors, and cookware specialists at America's Test Kitchen, a very real 2,500-square-foot kitchen located just outside Boston. Our mission is to find the very best recipes, ingredients, and kitchen equipment—we do the testing so you don't have to. Find us on our blog, public television, radio, or our many books and magazine publications. Go behind the scenes with us in the kitchen on twitter (@TestKitchen) and on Facebook.

4 Comments

  • ccwong.melom

    Water is so blag. Try one of these tasty Asian remedies: http://travel.cnn.com/asias-top-hangover-cures-230961

  • Barbara

    Unless those organic winemakers are somehow making unfermented wines, there ARE sulfites in them, albeit in very small amounts, which may allow the winemakers to legally label them as “sulfite free”. Sulfites are a natural byproduct of alcohol fermentation. There’s no such thing as a 100% “sulfite free” alcoholic wine. It might be better to state that there are no ADDED sulfites in organic wines.

  • Ty

    Dos this apply to bear at all too? Sometimes I get similar headaches from a single beer, but I’ve never heard about the cause as described for wine in the article above.

  • Ty

    And by “bear” I mean “beer”. . . :)

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